Article

Epigenome-wide Association Study of Alcohol Use Disorder in Five Brain Regions

2021-08-04

Abstract excerpt

Alcohol Use Disorder (AUD) is closely linked to the brain regions forming the neurocircuitry of addiction. Postmortem human brain tissue enables the direct study of the molecular pathomechanisms of AUD. This study aims to identify these mechanisms by examining differential DNA-methylation between cases with severe AUD (n=53) and controls (n=58) using a brain region-specific approach, in which sample sizes ranged b...

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Literature Corpus work: 7604b900-a413-5de0-8e2f-a02d1d7be335
DOI: 10.1101/2021.08.01.21261118

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