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Article

Alpha hemoglobin stabilizing protein: Its causal relationship with the severity of beta thalassemia.

Blood cells, molecules & diseases - 1 Aug 2015

Sagar Chandan S, Kumar Rakesh, Sharma Dharmesh C, Kishor Purnima

Abstract excerpt

Thalassemia major is characterized by anemia, iron overload and cellular damage. The severity of symptoms correlates with the alpha/non-alpha globin imbalance and is proportional to the magnitude of alpha chain excess. Alpha hemoglobin stabilizing protein (AHSP), the erythroid specific alpha globin chaperone, stabilizes free alpha chains, and prevents the formation of reactive oxygen radicals. Though AHSP...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26142324
DOI: 10.1016/j.bcmd.2015.05.005

Genes

AHSP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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