Article
A twins heritability study on alpha hemoglobin stabilizing protein (AHSP) expression variability.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Dec 2010
Lai Mei I, Garner Chad, Jiang Jie, Silver Nicholas, Best Steve, Menzel Stephan, Thein Swee L
Abstract excerpt
Cytotoxic precipitation of free α-globin monomers and its production of reactive oxygen species cause red cell membrane damage that leads to anemia and eventually ineffective erythropoiesis in β-thalassemia. Alpha hemoglobin stabilizing protein (AHSP) was found to bind only to free α-globin monom...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
