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Article

Population analysis of the alpha hemoglobin stabilizing protein (AHSP) gene identifies sequence variants that alter expression and function.

American journal of hematology - 1 Feb 2008

dos Santos Camila O, Zhou Suiping, Secolin Rodrigo, Wang Xiaomei, Cunha Anderson F, Higgs Douglas R, Kwiatkowski Janet L, Thein Swee Lay, Gallagher Patrick G, Costa Fernando F, Weiss Mitchell J

Abstract excerpt

Alpha-hemoglobin stabilizing protein (AHSP) is a potential modifier of beta-thalassemia by virtue of its ability to detoxify excess free alpha-globin. However, examination of patients with beta-thalassemia from a few geographic regions failed to identify obvious AHSP mutations. We extended these studies by analyzing AHSP gene sequences in 366 anonymous individuals from five different areas of the world. We...

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Source

Identifiers

PMID: 17874450
DOI: 10.1002/ajh.21041

Genes

AHSP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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