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Article

The miR-146a SNP Rs2910164 and miR-155 SNP rs767649 Are Risk Factors for Non-Small Cell Lung Cancer in the Iranian Population.

Canadian respiratory journal - 1 Jan 2020

Dezfuli Neda K, Adcock Ian M, Alipoor Shamila D, Seyfi Sharareh, Salimi Babak, Mafi Golchin Maryam, Dalil Roofchayee Neda, Varhram Mohammad, Mortaz Esmaeil

Abstract excerpt

Background: Lung cancer is one of the leading causes of death worldwide. MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression and may act as both tumor suppressors and as oncogenes. The presence of single nucleotide polymorphisms (SNPs) inside the miRNA genomic region could affect target miRNA maturation, expression, and binding to its target mRNA and contribute to cancer development....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33294082
DOI: 10.1155/2020/8179415
PMCID: PMC7700047

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