Article
Common variants of pro-inflammatory gene IL1B and interactions with PPP1R13L and POLR1G in relation to lung cancer among Northeast Chinese.
Scientific reports - 5 May 2023
Yin Jiaoyang, Wang Chunhong, Vogel Ulla, Ma Yegang, Zhang Ying, Wang Huiwen, Sun Zhenxiang, Du Shuai
Abstract excerpt
Lung cancer is a complex disease influenced by a variety of genetic and environmental factors. The cytokine interleukin 1 encoded by IL1B is an important mediator of the inflammatory response, and is involved in a variety of cellular activities. The effect of single nucleotide polymorphisms (SNP) at IL1B has been investigated in relation to cancer with inconsistent results. This Northeastern-Chinese case-control...
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