Article

Whole-genome bisulfite sequencing reveals the alteration of DNA methylation during malignant transformation of oral mucosal cells

2023-04-06

Abstract excerpt

<h4>Background: </h4> According to recent researches, the overall malignant transformation rate of oral potentially malignant disorders (OPMDs) is among 7.9%, and the probability of malignant transformation of OPMDs with severe epithelial dysplasia to oral squamous cell carcinoma (OSCC) is as high as 57%. In recent years, more and more studies have confirmed that abnormal DNA methylation, especially hypermethylati...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f4e75aad-77d1-59ad-a188-ff09e61cf296
DOI: 10.21203/rs.3.rs-2747089/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Whole-genome bisulfite sequencing reveals the alteration of DNA methylation during malignant transformation of oral mucosal cellsDOI 10.21203/rs.3.rs-2747089/v1Read

DNA Methylome Distinguishes Oropharyngeal and Oral Cancer from Oral Lesions and Healthy Oral MucosaSemantic proximity Read

Total RNA sequencing reveals gene expression and microbial alterations shared by oral pre-malignant lesions and cancerSemantic proximity Read

Genetic and molecular alterations associated with oral squamous cell cancer (Review).Semantic proximity Read

Genetics/epigenetics of oral premalignancy: current status and future research*Semantic proximity Read

Genetic and epigenetic alterations in the tumour, tumour margins, and normal buccal mucosa of patients with oral cancerSemantic proximity Read

Total RNA sequencing reveals gene expression and microbial alterations shared by oral pre-malignant lesions and cancerSemantic proximity Read

Current Insights into Oral Cancer Epigenetics.Semantic proximity Read

DNA methylation markers for oral pre-cancer progression: A critical reviewSemantic proximity Read

Genome‐wide DNA methylation profiling in tongue squamous cell carcinomaSemantic proximity Read

DNA methylation analysis by bisulfite next-generation sequencing for early detection of oral squamous cell carcinoma and high-grade squamous intraepithelial lesion from oral brushing.Semantic proximity Read

Genetic alterations and clinical dimensions of oral cancer: a review.Semantic proximity Read

DNA methylation and its potential roles in common oral diseasesSemantic proximity Read