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Article

p16 hypermethylation: a biomarker for increased esophageal cancer susceptibility in high incidence region of North East India.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2015

Das Mandakini, Saikia Bhaskar Jyoti, Sharma Santanu Kumar, Sekhon Gaganpreet Singh, Mahanta Jagadish, Phukan Rup Kumar

Abstract excerpt

Esophageal cancer is one of the most common cancers in North East India. The molecular mechanisms of esophageal cancer susceptibility in North East India have not been fully understood. There is a need for identification of biomarkers to identify people at risk of esophageal cancer. p16 is an essential G1 cell cycle regulatory gene whose loss of function is associated with carcinogenesis. Therefore, we conducted...

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PMID: 25361631
DOI: 10.1007/s13277-014-2762-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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