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Article

Assessment of copy number variations in the brain genome of schizophrenia patients

30 Jun 2015

Abstract excerpt

BACKGROUND: Cytogenomic mutations and chromosomal abnormality are implicated in the neuropathology of several brain diseases. Cell heterogeneity of brain tissues makes their detection and validation difficult, however. In the present study, we analyzed gene dosage alterations in brain DNA of schizophrenia patients and compared those with the copy number variations (CNVs) identified in schizophrenia patients as...

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PMID: 26136833
DOI: 10.1186/s13039-015-0144-5

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