Article
Copy Number Variations in Schizophrenia: Critical Review and New Perspectives on Concepts of Genetics and Disease
3 May 2010
Abstract excerpt
OBJECTIVE: Structural variations of DNA, such as copy number variations (CNVs), are recognized to contribute both to normal genomic variability and to risk for human diseases. For example, schizophrenia has an established connection with 22q11.2 deletions. Recent genome-wide studies have provided initial evidence that CNVs at other loci may also be associated with schizophrenia. In this article, the authors...
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