Article
The role of DNA copy number variation in schizophrenia.
Biological psychiatry - 1 Dec 2009
Tam Gloria W C, Redon Richard, Carter Nigel P, Grant Seth G N
Abstract excerpt
Schizophrenia is a major psychiatric disease with strong evidence of genetic risk factors. Recent studies based on genome-wide study of copy number variations (CNVs) have detected novel recurrent submicroscopic copy number changes, including recurrent deletions at 1q21.11, 15q11.3, 15q13.3, and the recurrent CNV at the 2p16.3 neurexin 1 locus. These schizophrenia susceptibility CNV loci demonstrate that...
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