Article
Genome-wide analysis shows increased frequency of copy number variation deletions in Dutch schizophrenia patients.
Biological psychiatry - 1 Oct 2011
Buizer-Voskamp Jacobine E, Muntjewerff Jan-Willem, Strengman Eric, Sabatti Chiara, Stefansson Hreinn, Vorstman Jacob A S, Ophoff Roel A
Abstract excerpt
BACKGROUND: Since 2008, multiple studies have reported on copy number variations (CNVs) in schizophrenia. However, many regions are unique events with minimal overlap between studies. This makes it difficult to gain a comprehensive overview of all CNVs involved in the etiology of schizophrenia. We performed a systematic CNV study on the basis of a homogeneous genome-wide dataset aiming at all CNVs ≥ 50 kilobase...
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