Article
Analysis of copy number variations in brain DNA from patients with schizophrenia and other psychiatric disorders.
Biological psychiatry - 15 Oct 2012
Ye Tianzhang, Lipska Barbara K, Tao Ran, Hyde Thomas M, Wang Liqin, Li Chao, Choi Kwang H, Straub Richard E, Kleinman Joel E, Weinberger Daniel R
Abstract excerpt
BACKGROUND: Clinical studies have identified several regions of the genome with copy number variations (CNVs) associated with diverse neurodevelopmental behavioral disorders. METHODS: We analyzed 1 million (M) single nucleotide polymorphism genotype arrays for evidence of previously reported recurrent CNVs and enriched genome-wide CNV burden in DNA from 600 brains, including 441 individuals with various...
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