Article
Bacillithiol has a role in Fe-S cluster biogenesis in Staphylococcus aureus.
Molecular microbiology - 1 Oct 2015
Rosario-Cruz Zuelay, Chahal Harsimranjit K, Mike Laura A, Skaar Eric P, Boyd Jeffrey M
Abstract excerpt
Staphylococcus aureus does not produce the low-molecular-weight (LMW) thiol glutathione, but it does produce the LMW thiol bacillithiol (BSH). To better understand the roles that BSH plays in staphylococcal metabolism, we constructed and examined strains lacking BSH. Phenotypic analysis found that the BSH-deficient strains cultured either aerobically or anaerobically had growth defects that were alleviated by the...
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