Article
Importance of bacillithiol in the oxidative stress response of Staphylococcus aureus.
Infection and immunity - 1 Jan 2014
Posada Ana C, Kolar Stacey L, Dusi Renata G, Francois Patrice, Roberts Alexandra A, Hamilton Chris J, Liu George Y, Cheung Ambrose
Abstract excerpt
In Staphylococcus aureus, the low-molecular-weight thiol called bacillithiol (BSH), together with cognate S-transferases, is believed to be the counterpart to the glutathione system of other organisms. To explore the physiological role of BSH in S. aureus, we constructed mutants with the deletion of bshA (sa1291), which encodes the glycosyltransferase that catalyzes the first step of BSH biosynthesis, and fosB...
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