Article
Analysis of mutants disrupted in bacillithiol metabolism in Staphylococcus aureus.
Biochemical and biophysical research communications - 28 Jun 2013
Rajkarnikar Arishma, Strankman Andrew, Duran Shayla, Vargas Derek, Roberts Alexandra A, Barretto Kathryn, Upton Heather, Hamilton Christopher J, Rawat Mamta
Abstract excerpt
Bacillithiol (BSH), an α-anomeric glycoside of l-cysteinyl-d-glucosaminyl-l-malate, is a major low molecular weight thiol found in low GC Gram-positive bacteria, such as Staphylococcus aureus. Like other low molecular weight thiols, BSH is likely involved in protection against a number of stresses. We examined S. aureus transposon mutants disrupted in each of the three genes associated with BSH biosynthesis....
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