Article
Functional FLT1 Genetic Variation is a Prognostic Factor for Recurrence in Stage I-III Non-Small-Cell Lung Cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jul 2015
Glubb Dylan M, Paré-Brunet Laia, Jantus-Lewintre Eloisa, Jiang Chen, Crona Daniel, Etheridge Amy S, Mirza Osman, Zhang Wei, Seiser Eric L, Rzyman Witold, Jassem Jacek, Auman Todd, Hirsch Fred R, Owzar Kouros, Camps Carlos, Dziadziuszko Rafal, Innocenti Federico
Abstract excerpt
BACKGROUND: We propose that single-nucleotide polymorphisms (SNPs) in genes of the vascular endothelial growth factor pathway of angiogenesis will associate with survival in non-small-cell lung cancer (NSCLC) patients. METHODS: Fifty-three SNPs in vascular endothelial growth factor-pathway genes were genotyped in 150 European stage I-III NSCLC patients and tested for associations with patient survival....
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