Article
Vascular endothelial growth factor receptor 2 gene polymorphisms as predictors for tumor recurrence and overall survival in non-small-cell lung cancer.
Annals of surgical oncology - 1 Jul 2012
Uzunoglu Faik G, Kaufmann Caroline, Wikman Harriet, Güngör Cenap, Bohn Benjamin A, Nentwich Michael F, Reeh Matthias, Pantel Klaus, Bockhorn Maximilian, Kutup Asad, Mann Oliver, Izbicki Jakob R, Vashist Yogesh K
Abstract excerpt
PURPOSE: VEGFR-2 gene displays several functional germline polymorphisms with impact on VEGFR-2 mediated angiogenesis. Our purpose was to evaluate VEGFR-2 polymorphisms as prognostic markers for tumor recurrence and overall survival (OS) in non-small-cell lung cancer (NSCLC). METHODS: In total, 209 Caucasian patients who had been surgically treated for NSCLC between 1996 and 2010 were included in this study....
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