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Article

Genotypes and haplotypes of the VEGF gene and survival in locally advanced non-small cell lung cancer patients treated with chemoradiotherapy.

BMC cancer - 16 Aug 2010

Guan Xiaoxiang, Yin Ming, Wei Qingyi, Zhao Hui, Liu Zhensheng, Wang Li-E, Yuan Xianglin, O'Reilly Michael S, Komaki Ritsuko, Liao Zhongxing

Abstract excerpt

BACKGROUND: Vascular endothelial growth factor (VEGF) is a major mediator of angiogenesis involving in carcinogenesis, including lung cancer. We hypothesized that VEGF polymorphisms may affect survival outcomes among locally advanced non-small cell lung cancer (LA-NSCLC) patients. METHODS: We genotyped three potentially functional VEGF variants [-460 T > C (rs833061), -634 G > C (rs2010963), and +936 C > T...

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Identifiers

PMID: 20712888
DOI: 10.1186/1471-2407-10-431
PMCID: PMC2939547

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Source receipt: pubmed, retrieved 7 Sept 2026.

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