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Article

Genetic variation in the coagulation factor V gene and risk of femoral head osteonecrosis.

Molecular medicine reports - 1 Sept 2015

Kim Tae-Ho, Baek Seung-Hoon, Lim Jeong Ok, Lee Sang-Han, Kim Shin-Yoon

Abstract excerpt

Osteonecrosis of the femoral head (ONFH) is characterized by the death of the cellular portion of the femoral head due a reduction or disruption in the blood supply. Certain studies have implicated coagulation disorders, including thrombophilia and hypofibrinolysis, in the pathogenesis of ONFH. The factor V (F5) Leiden mutation has been suggested to be a genetic risk factor for venous thromboembolism and...

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PMID: 26130054
DOI: 10.3892/mmr.2015.4000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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