Article
Lack of association of MTHFR gene polymorphisms with the risk of osteonecrosis of the femoral head in a Korean population.
Molecules and cells - 1 Apr 2010
Kim Tae-Ho, Hong Jung Min, Kim Hyun-Ju, Park Eui Kyun, Kim Shin-Yoon
Abstract excerpt
Some studies have suggested that coagulation disorders may be implicated in osteonecrosis of the femoral head (ONFH). The C677T polymorphism of the 5, 10-methylenetetrahydrofolate reductase (MTHFR) gene has been postulated to be a genetic risk factor for venous thromboembolism and osteonecrosis i...
Topics
- Adult
- Asian People
- Case-Control Studies
- Female
- Femur Head Necrosis
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Haplotypes
- Humans
- Korea
- Linkage Disequilibrium
- Logistic Models
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Middle Aged
- Polymorphism, Single Nucleotide
- Risk Factors