Article
Lack of association of MTHFR gene polymorphisms with the risk of osteonecrosis of the femoral head in a Korean population.
Molecules and cells - 1 Apr 2010
Kim Tae-Ho, Hong Jung Min, Kim Hyun-Ju, Park Eui Kyun, Kim Shin-Yoon
Abstract excerpt
Some studies have suggested that coagulation disorders may be implicated in osteonecrosis of the femoral head (ONFH). The C677T polymorphism of the 5, 10-methylenetetrahydrofolate reductase (MTHFR) gene has been postulated to be a genetic risk factor for venous thromboembolism and osteonecrosis in Caucasians, but this relationship has not been established in other populations. In this study, we conducted...
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