Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical Characterization and Molecular Analysis of Fourteen Chinese Patients with Factor V Deficiency.

Hamostaseologie - 1 Dec 2023

Zhang Ke, Ye Longying, Jin Yanhui, Chen Yuan, Zeng Manlin, Jia Kaiqi, Yang Lihong, Wang Mingshan

Abstract excerpt

INTRODUCTION: Coagulation factor V (FV) functions as a vital cofactor that performs procoagulant roles in the coagulation system. We investigated 14 unrelated patients whose plasma FV levels were all below the reference range. METHODS: FV activity (FV:C) and FV antigen were detected by one-stage clotting and ELISA, respectively. All 25 exons of the F5 gene in patients were amplified by the PCR, and they were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to China
Share to Factor V Deficiency
Share to Hemorrhage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homozygote

Share to Mutation

Share to Mutation, Missense

Source

Identifiers

PMID: 37714176
DOI: 10.1055/a-2146-9540

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical Characterization and Molecular Analysis of Fourteen Chinese Patients with Factor V Deficiency.PMID 37714176Read ↗

[The Clinical Phenotype and Molecular Pathogenic Mechanism of a Family with Hereditary Coagulation Factor V Deficiency].Semantic proximity Read ↗

A novel homozygous mutation (Gly1715Ser) causing hereditary factor V deficiency in a Chinese patient.Semantic proximity Read ↗

[Analysis of phenotype and genotype in four Chinese pedigrees with inherited coagulation factor V deficiency.].Semantic proximity Read ↗

A novel mutation (Ser951LeufsTer8) in F5 gene leads to hereditary coagulation factor V deficiency.Semantic proximity Read ↗

A Comprehensive Overview of Coagulation Factor V and Congenital Factor V DeficiencySemantic proximity Read ↗

Genetic Analysis of Hereditary Coagulation Factor V Deficiency in Two Chinese Families Caused by Compound Heterozygous Mutations.Semantic proximity Read ↗

Clinical, Laboratory, and Molecular Aspects of Factor V DeficiencySemantic proximity Read ↗

[Analysis of a Chinese pedigree affected with Hereditary factor Ⅴ deficiency due to compound heterozygous variants of F5 gene].Semantic proximity Read ↗

[Phenotypic and genetic analysis of a pedigree affected with hereditary FV deficiency due to a novel deletional variant of F5 gene].Semantic proximity Read ↗

Congenital factor V deficiency in Taiwan: identification of a novel variant p.Tyr1813 ∗ and two variants specific to East Asians.Semantic proximity Read ↗

Identification of three F5 gene mutations associated with inherited coagulation factor V deficiency in two Chinese pedigrees.Semantic proximity Read ↗

Molecular and clinical characterization of two unrelated families with factor V deficiency, including a novel nonsense variant (p.Gln1532*).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.