Article
Single nucleotide polymorphisms other than factor V Leiden are associated with coagulopathy and osteonecrosis of the femoral head in Chinese patients.
PloS one - 1 Jan 2014
Peng Kou-Ti, Huang Kuo-Chin, Huang Tsan-Wen, Lee Yun-Shien, Hsu Wei-Hsiu, Hsu Robert W W, Ueng Steve W N, Lee Mel S
Abstract excerpt
Single nucleotide polymorphisms (SNPs) of factor V Leiden have been associated with osteonecrosis of the femoral head (ONFH) in Caucasians but remains controversial in Asians. We used an SNP microarray to screen 55 loci of factor V gene in patients with ONFH of Chinese. Significantly different candidate SNPs at 14 loci were analyzed in 146 patients and 116 healthy controls using MALDI-TOF (matrix-assisted laser...
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