Article
Genetic background of nontraumatic osteonecrosis of the femoral head in the Korean population.
Clinical orthopaedics and related research - 1 May 2008
Chang Jun-Dong, Hur Mina, Lee Sang-Soo, Yoo Je-Hyun, Lee Kyu Man
Abstract excerpt
Major thrombophilic mutations have been identified as risk factors for nontraumatic osteonecrosis of the femoral head (ONFH) in Caucasians. We asked whether the genetic background of patients with ONFH in the Korean population was similar. We analyzed factor V G1691A mutation (factor V Leiden), prothrombin G20210A mutation, and methylenetetrahydrofolate reductase C677T and A1298C polymorphisms in 71 patients (53...
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