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Article

Association analysis of tissue factor pathway inhibitor polymorphisms and haplotypes with osteonecrosis of the femoral head in the Korean population.

Molecules and cells - 30 Nov 2008

Dai Xue Lian, Hong Jung Min, Oh Bermseok, Cho Yoon Shin, Lee Jong-Young, Park Eui Kyun, Kim Chang Yoon, Kim Shin-Yoon, Kim Tae-Ho

Abstract excerpt

Thrombophilia and hypofibrinolysis have been implicated in the pathogenesis of osteonecrosis of the femoral head (ONFH). Tissue factor pathway inhibitor (TFPI), a multivalent protease inhibitor, is an important regulator of the tissue factor-mediated blood coagulation pathway. Mutations of the TFPI gene can increase the risk of thrombin generation and venous thrombosis. The aim of this study was to evaluate the...

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PMID: 18695356

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TFPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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