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Article

Spatial Moran models, II: cancer initiation in spatially structured tissue.

Journal of mathematical biology - 1 Apr 2016

Durrett R, Foo J, Leder K

Abstract excerpt

We study the accumulation and spread of advantageous mutations in a spatial stochastic model of cancer initiation on a lattice. The parameters of this general model can be tuned to study a variety of cancer types and genetic progression pathways. This investigation contributes to an understanding of how the selective advantage of cancer cells together with the rates of mutations driving cancer, impact the process...

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Identifiers

PMID: 26126947
DOI: 10.1007/s00285-015-0912-1
PMCID: PMC4947874

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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