Article
Apelin polymorphism predicts blood pressure response to losartan in older Chinese women with essential hypertension.
Genetics and molecular research : GMR - 12 Jun 2015
Jia J, Men C, Tang K-T, Zhan Y-Y
Abstract excerpt
We determined whether the blood pressure response to losartan in an older Chinese population with essential hypertension was associated with apelin gene polymorphisms. We genotyped the -1860T>C polymorphism of the apelin gene in a case-control study of 222 patients with hypertension and 250 controls. Following 24 weeks of treatment with losartan (50 mg/day), reductions in systolic blood pressure were...
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