MicroRNA-765 influences arterial stiffness through modulating apelin expression.

doi:10.1016/j.mce.2015.04.006

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Article

MicroRNA-765 influences arterial stiffness through modulating apelin expression.

Molecular and cellular endocrinology - 15 Aug 2015

Liao Yi-Chu, Wang Yung-Song, Hsi Edward, Chang Ming-Hung, You Yun-Zhen, Juo Suh-Hang Hank

Abstract excerpt

The present study aims to discover single nucleotide polymorphisms (SNPs) at the apelin gene (APLN) in relation to arterial stiffness, and to explore its molecular mechanisms. A two-step genetic association study was conducted using 799 and 937 subjects in the screening and validation data, respectively. Four tagging SNPs of APLN were tested. SNP rs3115757 was significantly associated with stiffness parameters...

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PMID: 25882991
DOI: 10.1016/j.mce.2015.04.006

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APLN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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