Article
Family-based analysis of apelin and AGTRL1 gene polymorphisms with hypertension in Han Chinese.
Journal of hypertension - 1 Jun 2009
Li Wei-Wei, Niu Wen-Quan, Zhang Yi, Wu Shengnan, Gao Ping-Jin, Zhu Ding-Liang
Abstract excerpt
OBJECTIVE: Apelin and AGTRL1 (angiotensin receptor-like 1), elements of a newly identified pathway with a role in counter regulating the renin-angiotensin system, have been implicated in blood pressure regulation. This study aims to assess whether the apelin and AGTRL1 genetic polymorphisms might contribute to essential hypertension or its related phenotypes. METHODS: We recruited 1015 Han Chinese from 248...
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