Article
Analytical Validation of AmpliChip p53 Research Test for Archival Human Ovarian FFPE Sections.
PloS one - 1 Jan 2015
Marton Matthew J, McNamara Andrew R, Nikoloff D Michele, Nakao Aki, Cheng Jonathan
Abstract excerpt
The p53 tumor suppressor gene (TP53) is reported to be mutated in nearly half of all tumors and plays a central role in genome integrity. Detection of mutations in p53 can be accomplished by many assays, including the AmpliChip p53 Research Test. The AmpliChip p53 Research Test has been successfully used to determine p53 status in hematologic malignancies and fresh frozen solid tissues but there are few reports...
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