Article
The eNOS 894G/T gene polymorphism and its influence on early and long-term mortality after on-pump cardiac surgery.
Journal of cardiothoracic surgery - 25 Oct 2013
Hinz José, Schöndorf Daniel, Bireta Christian, Lipke Christina, Moerer Onnen, Bergmann Ingo, Wiese Christoph Herman, Mansur Ashham, Schotola Hanna, Sabashnikov Anton, Quintel Michael, Schoendube Friedrich Albert, Popov Aron Frederik
Abstract excerpt
BACKGROUND: The eNOS 894G/T polymorphism (GG, GT, and TT) is associated with cardiovascular mortality and may influence cardiovascular diseases as a genetic risk factor. Moreover, this polymorphism has an impact on intraoperative hemodynamics during cardiac surgery with cardiopulmonary bypass (CPB). In this study, we analyzed the influence of this gene polymorphism on early clinical outcome in patients who...
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