Article
Anthocyanin-rich Seoritae extract ameliorates renal lipotoxicity via activation of AMP-activated protein kinase in diabetic mice.
Journal of translational medicine - 27 Jun 2015
Koh Eun Sil, Lim Ji Hee, Kim Min Young, Chung Sungjin, Shin Seok Joon, Choi Bum Soon, Kim Hye Won, Hwang Seong Yeon, Kim Sae Woong, Park Cheol Whee, Chang Yoon Sik
Abstract excerpt
BACKGROUND: Anthocyanins are major constituents of food colours and have been reported to possess anti-diabetic activities for potential medicinal use. The precise role of anthocyanins in diabetic nephropathy is poorly understood. We investigated whether anthocyanin-rich Seoritae extract (SE) can potentially prevent oxidative stress and lipotoxicity, which are the main causes of renal damage in diabetic...
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