Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Does the Concentration of Oxidative and Inflammatory Biomarkers Differ by Haptoglobin Genotype in Type 1 Diabetes?

Antioxidants & redox signaling - 20 Dec 2015

Costacou Tina, Evans Rhobert W, Orchard Trevor J

Abstract excerpt

The haptoglobin (Hp) 2 allele directly predicts coronary artery disease in type 1 diabetes, potentially due to its decreased antioxidative/anti-inflammatory properties. We measured the concentrations of oxidative/inflammatory biomarkers (urinary 15-isoprostane F(2t) [IsoP], α- and γ-tocopherol, tumor necrosis factor α [TNF-α], high-sensitivity C-reactive protein [hsCRP], white blood cell [WBC] count, fibrinogen,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Biomarkers
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Follow-Up Studies

Share to Haptoglobins

Share to Leukocyte Count

Share to Oxidative Stress

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 26114833
DOI: 10.1089/ars.2015.6355
PMCID: PMC4692105

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Does the Concentration of Oxidative and Inflammatory Biomarkers Differ by Haptoglobin Genotype in Type 1 Diabetes?PMID 26114833Read ↗

Is it time to screen for the haptoglobin genotype to assess the cardiovascular risk profile and vitamin E therapy responsiveness in patients with diabetes?Semantic proximity Read ↗

Haptoglobin genotype: a determinant of cardiovascular complication risk in type 1 diabetes.Semantic proximity Read ↗

Vitamin E therapy results in a reduction in HDL function in individuals with diabetes and the haptoglobin 2-1 genotype.Semantic proximity Read ↗

Divergent effects of alpha-tocopherol and vitamin C on the generation of dysfunctional HDL associated with diabetes and the Hp 2-2 genotype.Semantic proximity Read ↗

Haptoglobin 2-2 genotype is not associated with cardiovascular risk in subjects with elevated glycohemoglobin-results from the Bruneck Study.Semantic proximity Read ↗

Application of pharmacogenomics in the prevention of diabetic cardiovascular disease: mechanistic basis and clinical evidence for utilization of the haptoglobin genotype in determining benefit from antioxidant therapy.Semantic proximity Read ↗

Haptoglobin: basic and clinical aspects.Semantic proximity Read ↗

Haptoglobin genotype is associated with increased endothelial dysfunction serum markers in type 1 diabetes.Semantic proximity Read ↗

Distinct Cardiometabolic Profiles for Overweight/Obese People with Different Haptoglobin Phenotypes: A Cross-Sectional StudySemantic proximity Read ↗

Correction of HDL dysfunction in individuals with diabetes and the haptoglobin 2-2 genotype.Semantic proximity Read ↗

Effect of vitamin E supplementation on HDL function by haptoglobin genotype in type 1 diabetes: results from the HapE randomized crossover pilot trial.Semantic proximity Read ↗

Haptoglobin Phenotype Modulates Lipoprotein-Associated Risk for Preeclampsia in Women With Type 1 Diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.