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Correction of HDL dysfunction in individuals with diabetes and the haptoglobin 2-2 genotype.

Diabetes - 1 Oct 2008

Asleh Rabea, Blum Shany, Kalet-Litman Shiri, Alshiek Jonia, Miller-Lotan Rachel, Asaf Roy, Rock Wasseem, Aviram Michael, Milman Uzi, Shapira Chen, Abassi Zaid, Levy Andrew P

Abstract excerpt

OBJECTIVE: Pharmacogenomics is a key component of personalized medicine. The Israel Cardiovascular Events Reduction with Vitamin E Study, a prospective placebo-controlled study, recently demonstrated that vitamin E could dramatically reduce CVD in individuals with diabetes and the haptoglobin (Hp) 2-2 genotype (40% of diabetic individuals). However, because of the large number of clinical trials that failed to...

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Share to Antioxidants
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haptoglobins

Share to Lipoproteins, HDL

Share to Models, Biological

Share to Oxidation-Reduction

Share to Vitamin E

Source

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Identifiers

PMID: 18599520
DOI: 10.2337/db08-0450
PMCID: PMC2551691

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