Article
Haptoglobin 2-2 genotype is not associated with cardiovascular risk in subjects with elevated glycohemoglobin-results from the Bruneck Study.
Journal of the American Heart Association - 16 May 2014
Pechlaner Raimund, Kiechl Stefan, Willeit Peter, Demetz Egon, Haun Margot, Weger Siegfried, Oberhollenzer Friedrich, Kronenberg Florian, Bonora Enzo, Weiss Günter, Willeit Johann
Abstract excerpt
BACKGROUND: Haptoglobin (Hp) is an abundant plasma protein with antioxidant properties. The Hp 2-2 genotype has previously been linked to coronary heart disease risk in individuals with elevated glycosylated hemoglobin (HbA1c). We investigated the association of Hp and HbA1c with cardiovascular disease (CVD) in the longitudinal, population-based Bruneck Study. METHODS AND RESULTS: Hp genotype was determined by...
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