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Article

Sequence-Based Predictive Models of Resistance to HIV-1 Integrase Inhibitors: An n-Grams Approach to Phenotype Assessment.

Current HIV research - 1 Jan 2015

Masso Majid

Abstract excerpt

Amino acid substitutions in HIV-1 proteins critical to the viral replication cycle have the potential to undermine successful inhibition of those targets, with some mutations leading to either reduced susceptibility to certain medications or complete drug resistance. Phenotypic tests are best suited to quantify the effects of complex mutational patterns on drug resistance; however, the relatively high cost and...

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Identifiers

PMID: 26105155
DOI: 10.2174/1570162x13666150624100535

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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