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Article

Sequence and structure based models of HIV-1 protease and reverse transcriptase drug resistance.

BMC genomics - 1 Jan 2013

Masso Majid, Vaisman Iosif I

Abstract excerpt

BACKGROUND: Successful management of chronic human immunodeficiency virus type 1 (HIV-1) infection with a cocktail of antiretroviral medications can be negatively affected by the presence of drug resistant mutations in the viral targets. These targets include the HIV-1 protease (PR) and reverse transcriptase (RT) proteins, for which a number of inhibitors are available on the market and routinely prescribed....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24268064
DOI: 10.1186/1471-2164-14-S4-S3
PMCID: PMC3849442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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