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Article

Rapid and quantitative method of allele-specific DNA methylation analysis.

BioTechniques - 1 Dec 2006

Wong Hui-Lee, Byun Hyang-Min, Kwan Jennifer M, Campan Mihaela, Ingles Sue A, Laird Peter W, Yang Allen S

Abstract excerpt

Several biological phenomena depend on differential methylation of chromosomal strands. While understanding the role of these processes requires information on allele-specific methylation, the available methodologies are not quantitative or labor-intensive. We describe a novel, rapid method to quantitate allele-specific DNA methylation based on the combination of bisulfite PCR and Pyrosequencing. In this method,...

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PMID: 17191619
DOI: 10.2144/000112305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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