Article
Differentiation of Human-Induced Pluripotent Stem Cells Into Insulin-Producing Clusters by MicroRNA-7.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation - 1 Oct 2016
Shaer Anahita, Azarpira Negar, Karimi Mohammad Hosein, Soleimani Masood, Dehghan Sadrollah
Abstract excerpt
OBJECTIVES: Diabetes results from inadequate insulin production from pancreatic β-cells. Islet cell replacement is an effective approach for diabetes treatment; however, it is not sufficient for all diabetic patients. Thus, finding a new source with effective maturation of β-cells is the major goal of many studies. MicroRNAs are a class of small noncoding ribonucleic acid that regulate gene expression through...
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