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Pancreatic islet differentiation of human embryonic stem cells by microRNA overexpression

30 Jul 2013

Abstract excerpt

Development of stem cell-based therapies for the treatment of type 1 diabetes would provide a renewable supply of human β-cells. Human embryonic stem cells (ESCs) are considered to be one of the stem cell populations with sufficient proliferative capacity to achieve this goal. Currently, differentiation protocols directing ESCs toward a pancreatic fate employ a variety of expensive cytokines and inhibitors. With...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23897763
DOI: 10.1002/term.1787

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