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Article

Three-Dimensional Differentiation of Embryonic Stem Cells into Islet-like Insulin-Producing Clusters

12 Feb 2009

Abstract excerpt

The production of mature pancreatic cells that function similarly to primary islets is the premise of cell therapy for diabetes. Here, we describe a novel approach to generating more mature insulin-producing cells from embryonic stem (ES) cells. A three-dimensional (3D) ES cell pancreatic differentiation system was developed and used to direct the ES cell differentiation into glucose-responsive, insulin-secreting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19196138
DOI: 10.1089/ten.tea.2008.0181

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