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Article

A Fas associated factor negatively regulates anti-bacterial immunity by promoting Relish degradation in Bombyx mori.

Insect biochemistry and molecular biology - 1 Aug 2015

Ma Xiaojuan, Li Xianyang, Dong Shifeng, Xia Qingyou, Wang Fei

Abstract excerpt

Negative regulation is required to keep NF-κB-dependent immune response under tight control. In previous study, we have identified a Fas associated factor (FAF) family member in Bombyx mori, BmFAF, and proposed it may act as a negative regulator in immune response. In this study, we found knock-down of BmFAF by RNAi led to a remarkable increase in transcriptional level of several antimicrobial peptide genes,...

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PMID: 26101847
DOI: 10.1016/j.ibmb.2015.06.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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