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Article

fat facets induces polyubiquitination of Imd and inhibits the innate immune response in Drosophila.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Nov 2013

Yagi Yoshimasa, Lim Young-Mi, Tsuda Leo, Nishida Yasuyoshi

Abstract excerpt

The IMD pathway is one of the major regulators of the innate immune response in Drosophila. Although extensive analysis of the IMD pathway has been carried out, precise mechanisms for how each target gene of the pathway is down-regulated remain to be clarified. Here, we carried out genetic screening and found that fat facets (faf), which encodes a deubiquitinating enzyme, inhibited the expression of the target...

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PMID: 23919485
DOI: 10.1111/gtc.12085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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