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Article

Integrative genome-wide analysis reveals HLP1, a novel RNA-binding protein, regulates plant flowering by targeting alternative polyadenylation.

Cell research - 1 Jul 2015

Zhang Yong, Gu Lianfeng, Hou Yifeng, Wang Lulu, Deng Xian, Hang Runlai, Chen Dong, Zhang Xiansheng, Zhang Yi, Liu Chunyan, Cao Xiaofeng

Abstract excerpt

Alternative polyadenylation (APA) is a widespread mechanism for gene regulation and has been implicated in flowering, but the molecular basis governing the choice of a specific poly(A) site during the vegetative-to-reproductive growth transition remains unclear. Here we characterize HLP1, an hnRNP A/B protein as a novel regulator for pre-mRNA 3'-end processing in Arabidopsis. Genetic analysis reveals that HLP1...

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Identifiers

PMID: 26099751
DOI: 10.1038/cr.2015.77
PMCID: PMC4493284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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