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Article

Genome-Wide Analysis of PAPS1-Dependent Polyadenylation Identifies Novel Roles for Functionally Specialized Poly(A) Polymerases in Arabidopsis thaliana.

PLoS genetics - 1 Aug 2015

Kappel Christian, Trost Gerda, Czesnick Hjördis, Ramming Anna, Kolbe Benjamin, Vi Son Lang, Bispo Cláudia, Becker Jörg D, de Moor Cornelia, Lenhard Michael

Abstract excerpt

The poly(A) tail at 3' ends of eukaryotic mRNAs promotes their nuclear export, stability and translational efficiency, and changes in its length can strongly impact gene expression. The Arabidopsis thaliana genome encodes three canonical nuclear poly(A) polymerases, PAPS1, PAPS2 and PAPS4. As shown by their different mutant phenotypes, these three isoforms are functionally specialized, with PAPS1 modifying organ...

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Identifiers

PMID: 26305463
DOI: 10.1371/journal.pgen.1005474
PMCID: PMC4549238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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