Article
Optimization of Tumor Dissection Procedures Leads to Measurable Improvement in the Quality of Molecular Testing.
The Journal of molecular diagnostics : JMD - 1 Oct 2024
Betz Bryan L, Post Corey S, Bergendahl Jennifer, Lefebvre Nanci, Weigelin Helmut, Brown Noah A
Abstract excerpt
Molecular tests have an inherent limit of detection (LOD) and, therefore, require samples with sufficiently high percentages of neoplastic cells. Many laboratories use tissue dissection; however, optimal procedures for dissection and quality assurance measures have not been established. In this study, several modifications to tissue dissection procedures and workflow were introduced over 4 years. Each...
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