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Article

Impact of serous fluid volume on next-generation sequencing: a significant step forward for optimization of serous fluid sample collection.

Journal of the American Society of Cytopathology - 1 Jan 2024

Beg Shaham, Xu Kemin, Solomon James P, Alperstein Susan A, Siddiqui Momin T

Abstract excerpt

INTRODUCTION: Current literature lacks data regarding the influence of serous fluid volume (SFV) on next-generation sequencing (NGS) performed on malignant cases. In this study, we highlight the impact of SFV and other parameters influencing the outcome of NGS analysis. MATERIALS AND METHODS: We evaluated 827 samples of serous fluids from 607 patients. Of these, 72 samples underwent NGS analysis. Effusion volume,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Biomarkers, Tumor

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Share to Pleural Effusion, Malignant

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Source

Identifiers

PMID: 39068145
DOI: 10.1016/j.jasc.2024.07.001

Genes

ALK
EGFR
KRAS
NTRK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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