Article
Association of IL-1α rs17561 and IL-1 RN rs315952 polymorphisms with Tourette syndrome: a family-based study.
International journal of clinical and experimental pathology - 1 Jan 2015
He Fan, Shao Xiaohui, Yi Mingji, Wang Yu, Wang Chuan-Yue, Liu Shiguo
Abstract excerpt
AIM: Immune system dysregulation has been implicated to play a key role in pathogenesis of Tourette syndrome (TS). IL-1α and IL-1RN are important inflammatory cytokines that mediate the inflammation. In this study, we investigated the relationship between single-nucleotide polymorphisms (SNPs) of IL-1α and IL-1RN and the susceptibility to TS in Chinese Han population. METHODS: A total of 276 children with TS and...
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