Article
Polymorphisms of interleukin 1 gene IL1RN are associated with Tourette syndrome.
Pediatric neurology - 1 May 2010
Chou I-Ching, Lin Hung-Chih, Wang Chung-Hsing, Lin Wei-De, Lee Cheng-Chun, Tsai Chang-Hai, Tsai Fuu-Jen
Abstract excerpt
Tourette syndrome has a multifactorial etiology in which genetic, environmental, and immunologic factors interact to establish vulnerability. Various interleukin 1 genes are associated with several immunoinflammatory diseases. It is not known whether polymorphisms in those genes are involved in the pathogenesis of Tourette syndrome. In this association study, single nucleotide polymorphisms were used to...
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