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Article

ASH1L may contribute to the risk of Tourette syndrome: Combination of family-based analysis and case-control study.

Brain and behavior - 1 Apr 2022

Liu Wenmiao, Xu Lulu, Zhang Cheng, Shen Lu, Dong Jicheng, Zhang Han, Liu Shiguo, Che Fengyuan, Zheng Xueping

Abstract excerpt

OBJECTIVE: Tourette syndrome (TS) is a childhood neurodevelopmental disorder caused by various genetic and environmental factors and presents with apparent genetic heterogeneity. As ASH1L potentially contributes to neurodevelopmental diseases, especially in TS, we aim to investigate the susceptibility of ASH1L on TS in the Chinese Han population. METHODS: Three tag single nucleotide polymorphisms (SNPs)...

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PMID: 35307981
DOI: 10.1002/brb3.2539
PMCID: PMC9014991

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